Newcastle boss Eddie Howe said his side are dangerously close to not being able to field a team for their Premier League game at Everton on 30 December.
Before the 1-1 draw with Manchester United on Monday, Howe said his squad was stretched and had a mixture of injuries and Covid-19 cases.
Forwards Callum Wilson and Allan Saint-Maximin both then suffered injuries during the game at St James’ Park.
Howe fears Wilson could be facing months on the sidelines.
Newcastle is 19th in the table, two points behind 17th-placed Watford.